Page 3 - nadann Galerie KW 21/03 VitaminDforAll

na dann... 03/2021
with increased risk at levels < 30ng/ml (75nmol/L) and severely greater risk < 20ng/ ml (50nmol/L).1
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1 The evidence was comprehensively reviewed (188 papers) through mid-June [Benskin ‘20] & more recent publications are increasingly compelling [Merzon et al ‘20; Kaufman et al ‘20; Castillo et al ‘20]. (See also [Jungreis & Kellis ‘20] for deeper analysis of Castillo et al’s RCT results.)
2 E.g.: 20ng/ml: National Academy of Medici- ne (US, Canada), European Food Safety Autho- rity, Germany, Austria, Switzerland, Nordic Countries, Australia, New Zealand, & consen- sus of 11 international organizations. 30ng/ml: Endocrine Society, American Geriatrics Soc., & consensus of scientific experts. See also [Bouillon ‘17].
3 [Palacios & Gonzalez ‘14; Cashman et al ‘16; van Schoor & Lips ‘17] Applies to China, India, Europe, US, etc.
4 [Heaney et al ‘15; Veugelers & Ekwaru ‘14]
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Evidence to date suggests the possibility that the COVID-19 pandemic sustains itself in large part through infection of those with low vi- tamin D, and that deaths are concentrated largely in those with deficiency. The mere pos- sibility that this is so should compel urgent gathering of more vitamin D data. Even wit- hout more data, the preponderance of evi- dence indicates that increased vitamin D
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would help reduce infections, hospitalizations, ICU admissions, & deaths.
Decades of safety data show that vitamin D has very low risk: Toxicity would be extreme- ly rare with the recommendations here. The risk of insufficient levels far outweighs any risk from levels that seem to provide most of the protection against COVID-19, and this is notably different from drugs. Vitamin D is much safer than steroids, such as dexametha- sone, the most widely accepted treatment to have also demonstrated a large COVID-19 be- nefit. Vitamin D’s safety is more like that of face masks. There is no need to wait for fur- ther clinical trials to increase use of something so safe, especially when remedying high rates of deficiency/insufficiency should already be a priority.
Therefore, we call on all governments, doc- tors, and healthcare workers worldwide to immediately recommend and implement ef- forts appropriate to their adult populations to increase vitamin D, at least until the end of the pandemic. Specifically to:
Recommend amounts from all sources suf- ficient to achieve 25(OH)D serum levels over 30ng/ml (75nmol/L), a widely endorsed mini- mum with evidence of reduced COVID-19 risk.
Recommend to adults vitamin D intake of 4000 IU (100mcg) daily (or at least 2000 IU) in the absence of testing. 4000 IU is widely regarded as safe.5
Recommend that adults at increased risk of deficiency due to excess weight, dark skin, or living in care homes may need higher intakes (eg, 2x). Testing can help to avoid levels too low or high.